Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282437 | 0.81 | ACACB (0.36) | ACACBCNR2 | |
| SCHEMBL5282939 | 0.78 | MAPT (0.42) | ACACB | |
| SCHEMBL4706606 | 0.73 | MAOA (0.33) | — | |
| SCHEMBL19510600 | 0.73 | FFAR4 (0.41) | ACACB | |
| SCHEMBL236762 | 0.73 | KDM4E (0.35) | — | |
| SCHEMBL238837 | 0.72 | MAOA (0.32) | ACACB | |
| SCHEMBL239087 | 0.72 | MAOA (0.32) | ACACB | |
| SCHEMBL240100 | 0.71 | KDM4E (0.46) | PDE3BPDE3A | |
| SCHEMBL29209046 | 0.71 | KDM4E (0.46) | PDE3BPDE3A | |
| SCHEMBL3563045 | 0.71 | SCN9A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004049-A1 | OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-11 | — | — | WO | disclosed |