Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555675 | 1.00 | HCAR2 (0.69) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL5284814 | 1.00 | HCAR2 (0.69) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL22619937 | 0.92 | ATM (0.77) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL2946078 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL2946075 | 0.91 | HCAR2 (0.59) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL448454 | 0.91 | HCAR2 (0.82) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL448456 | 0.91 | HCAR2 (0.82) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL322228 | 0.91 | HCAR2 (0.82) | HCAR2ATMKEAP1NFE2L2MAPT | |
| SCHEMBL4934756 | 0.88 | HCAR2 (0.78) | HCAR2ATMKEAP1NFE2L2MAPT | |
| Hydrochloric Acid SCHEMBL28061109 | 0.88 | HCAR2 (0.78) | HCAR2ATMKEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496521-A | Preparation method of aqueous polyaspartic acid ester resin emulsion with high wettability | 宝力新材料(宁国)有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-117625116-A | Polyaspartic acid ester resin joint beautifying agent | 宝力科技(宁国)有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117487109-A | Preparation method of water-based polyaspartic acid ester resin | 宝力科技(宁国)有限公司 | 2024-02-02 | — | — | CN | claimed |
| WO-2023123747-A1 | HYDROGEN ABSTRACTION PHOTOINITIATOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州鹿山光电材料有限公司 | 2023-07-06 | — | — | WO | claimed |
| CN-110183335-B | Method for preparing polyaspartic acid ester | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-110981741-A | Method for preparing polyaspartic acid ester | 万华化学集团股份有限公司 | 2020-04-10 | — | — | CN | claimed |
| US-6737500-B1 | RAPID REACTION OF FUMARIC ESTER WITH CYCLIC AMINE THEN WITH ACYCLIC AMINE | BAYER POLYMERS LLC | 2004-05-18 | — | — | US | claimed |
| EP-1210319-B1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | BAYER AG (US) | 2003-11-05 | — | — | EP | claimed |
| EP-1208135-B1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | BAYER AG (US) | 2003-10-01 | — | — | EP | claimed |
| US-6590066-B1 | Reacting polyoxyalkylene amines with ester of fumaric or maleic acid, then mixing acyclic amines to react with excess esters | BAYER CORPORATION | 2003-07-08 | — | — | US | claimed |
| EP-1210319-A1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | Bayer Corporation (US) | 2002-06-05 | — | — | EP | claimed |
| EP-1208135-A1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | Bayer Corporation (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001007504-A1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | BAYER CORPORATION (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007399-A1 | IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE | BAYER CORPORATION (US) | 2001-02-01 | — | — | WO | claimed |
| US-12152161-B2 | Polyurea compositions from polyaspartic esters and secondary heterocyclic amines derived aspartic esters | EVONIK OPERATIONS GMBH (DE) | 2024-11-26 | — | — | US | disclosed |
| US-20240376343-A1 | POLYUREA COMPOSITIONS FROM POLYASPARTIC ESTERS AND 2-SUBSTITUTED BUTANEDIOIC ACID ESTERS | EVONIK OPERATIONS GMBH (DE) | 2024-11-14 | — | — | US | disclosed |
| CN-118703109-A | Self-spraying polyurethane waterproof anticorrosive paint and preparation method thereof | 南宁市雨宇建筑装饰工程有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-0131419-B1 | CURING AGENT AND FLUOROCARBON POLYMER COATING COMPOSITION CONTAINING CURING AGENT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4517378-A | WEAR AND CORROSION RESISTANT COATINGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0131419-A1 | Curing agent and fluorocarbon polymer coating composition containing curing agent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376343-A1 | POLYUREA COMPOSITIONS FROM POLYASPARTIC ESTERS AND 2-SUBSTITUTED BUTANEDIOIC ACID ESTERS | BCKDK, PKD1, DERA | HCAR2 830/4885ATM 1969/4885KEAP1 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.