Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071443 | 0.88 | EPHX1 (0.76) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL14363235 | 0.87 | TP53 (0.81) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL16119683 | 0.86 | EPHX1 (0.81) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL21771978 | 0.85 | KMT2A (0.67) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL29826604 | 0.85 | TP53 (0.83) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL13561126 | 0.85 | HDAC1 (0.79) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL12368198 | 0.85 | KCNMA1 (0.79) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14363233 | 0.85 | TP53 (0.68) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL8358105 | 0.85 | TP53 (0.83) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL7828780 | 0.84 | KMT2A (0.72) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| US-8507546-B2 | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases | INSTITUTO DE MEDICINA MOLECULAR, FACULDADE DE MEDICINA DA UNIVERSIDADE DE LISBOA (PT) | 2013-08-13 | — | — | US | disclosed |