SCHEMBL21771978

SCHEMBL21771978

Cc1ccc(OC(=O)c2ccccc2)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.67
MEN1 O00255 7/20 0.67
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
CYP1A2 P05177 2/20 0.67
CYP2C9 P11712 2/20 0.67
CYP2C19 P33261 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
KCNMA1 Q12791 1/20 0.62
MAPT P10636 2/20 0.59
LMNA P02545 3/20 0.55
NR1I2 O75469 1/20 0.55
TP53 P04637 1/20 0.55
AHR P35869 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
ALDH1A1 P00352 2/20 0.54
CYP3A4 P08684 1/20 0.54
HDAC1 Q13547 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528361 0.85 HDAC1 (0.70) KMT2AMEN1SMN1; SMN2KCNMA1MAPT
SCHEMBL21771975 0.84 KMT2A (0.55) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL18668301 0.83 MAPT (0.55) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL21771940 0.83 KMT2A (0.76) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL7372747 0.82 KMT2A (0.62) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL16685068 0.82 KMT2A (0.77) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL16317646 0.80 KCNMA1 (0.76) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL498193 0.80 KMT2A (0.53) KMT2AMEN1SMN1; SMN2MAPTALDH1A1
SCHEMBL7327340 0.80 KMT2A (0.54) KMT2AMEN1NPC1RAB9ACYP1A2
SCHEMBL9196352 0.80 MEN1 (0.67) KMT2AMEN1SMN1; SMN2MAPTAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed