Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283624 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5278485 | 0.90 | MAPT (0.60) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5278490 | 0.90 | MAPT (0.60) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5281427 | 0.85 | MAPT (0.46) | MAPTSMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL5281425 | 0.85 | MAPT (0.46) | MAPTSMN1; SMN2HPGDKDM4EPOLB | |
| SCHEMBL4614949 | 0.81 | MAPT (0.49) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL4614943 | 0.81 | MAPT (0.49) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5283946 | 0.79 | ALDH1A1 (0.48) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5283941 | 0.79 | ALDH1A1 (0.48) | MAPTSMN1; SMN2HPGDKDM4EHSD17B10 | |
| SCHEMBL5287339 | 0.74 | RAB9A (0.46) | MAPTSMN1; SMN2KDM4ETP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KOYO SEIKO CO., LTD. (JP) | 2006-04-06 | — | — | US | claimed |
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-7294151-B2 | Means and method for dyeing keratin fibres | WELLA AG (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KOYO SEIKO CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
| EP-1599178-A1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078151-A1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KRT18, KLK5, KIT | MAPT 1807/4885SMN1; SMN2 3523/4885HPGD 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.