SCHEMBL5283660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5278495	1.00	ALOX5 (0.43)	ALOX5TP53MDM2BACE1THRB
	SCHEMBL5283048	0.86	MAPT (0.39)	TP53MDM2CNR1MAPTALDH1A1
	SCHEMBL5283041	0.86	MAPT (0.39)	TP53MDM2CNR1MAPTALDH1A1
	SCHEMBL4614942	0.83	ALOX5 (0.44)	ALOX5TP53MDM2THRBCNR1
	SCHEMBL4614941	0.83	ALOX5 (0.44)	ALOX5TP53MDM2THRBCNR1
	SCHEMBL5298282	0.78	ALDH1A1 (0.37)	ALOX5MAPTALDH1A1KDM4ELMNA
	SCHEMBL4615813	0.76	ALOX5 (0.47)	ALOX5TP53MDM2BACE1CNR1
	SCHEMBL5287532	0.69	MAPT (0.49)	THRBMAPTALDH1A1LMNA
	SCHEMBL4613802	0.68	PDE7A (0.40)	TP53MDM2MAPTALDH1A1KDM4E
	SCHEMBL4613804	0.68	PDE7A (0.40)	TP53MDM2MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.