SCHEMBL5283709

SCHEMBL5283709

CC(C)=NN=c1sc(-c2ccccc2)c(-c2ccccc2)n1CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
DPP4 P27487 2/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
FABP4 P15090 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5291224 1.00 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2DPP4KDM4EHPGD
SCHEMBL5293037 0.83 MAPT (0.34) ALDH1A1SMN1; SMN2KDM4EHPGDLMNA
SCHEMBL5281004 0.83 MAPT (0.34) ALDH1A1SMN1; SMN2KDM4EHPGDLMNA
SCHEMBL4613519 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2DPP4KDM4EHPGD
SCHEMBL4613516 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2DPP4KDM4EHPGD
SCHEMBL5283752 0.81 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2KDM4EHPGDLMNA
SCHEMBL5286732 0.81 TSHR (0.40) ALDH1A1SMN1; SMN2KDM4ETSHRTDP1
SCHEMBL5286269 0.80 PTGS1 (0.31) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL5285754 0.80 PTGS1 (0.31) ALDH1A1KDM4EHPGDLMNAHSD17B10
SCHEMBL5298282 0.78 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2KDM4EHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US claimed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US claimed
EP-1599178-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2005-11-30 EP claimed
WO-2004078151-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2004-09-16 WO claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP disclosed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US disclosed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060070190-A1 Means and method for dyeing keratin fibres KRT18, KLK5, KIT ALDH1A1 454/4885SMN1; SMN2 3523/4885DPP4 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.