SCHEMBL5283752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5283755	1.00	ALDH1A1 (0.37)	ALDH1A1KDM4EHPGDHSD17B10HTT
	SCHEMBL5281004	0.82	MAPT (0.34)	ALDH1A1KDM4EHPGDHSD17B10HTT
	SCHEMBL5293037	0.82	MAPT (0.34)	ALDH1A1KDM4EHPGDHSD17B10HTT
	SCHEMBL5283709	0.81	ALDH1A1 (0.35)	ALDH1A1KDM4EHPGDHSD17B10MAPT
	SCHEMBL5291224	0.81	ALDH1A1 (0.35)	ALDH1A1KDM4EHPGDHSD17B10MAPT
	SCHEMBL4614043	0.80	ALDH1A1 (0.41)	ALDH1A1KDM4EHPGDHSD17B10HTT
	SCHEMBL4614045	0.80	ALDH1A1 (0.41)	ALDH1A1KDM4EHPGDHSD17B10HTT
	SCHEMBL5286732	0.80	TSHR (0.40)	ALDH1A1KDM4EHTTPOLBKMT2A
	SCHEMBL5286739	0.80	TSHR (0.40)	ALDH1A1KDM4EHTTPOLBKMT2A
	SCHEMBL5298282	0.77	ALDH1A1 (0.37)	ALDH1A1KDM4EHPGDHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.