Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2684134 | 1.00 | REN (0.36) | RENALDH1A1GBA1 | |
| SCHEMBL5280625 | 0.86 | REN (0.34) | REN | |
| SCHEMBL2339221 | 0.86 | REN (0.34) | REN | |
| SCHEMBL2683172 | 0.86 | REN (0.34) | REN | |
| SCHEMBL5280813 | 0.82 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL2682948 | 0.82 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL6626149 | 0.68 | REN (0.42) | RENALDH1A1GBA1 | |
| SCHEMBL23752938 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL23752940 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL23752936 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863763-A1 | 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | Speedel Experimenta AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103275-A1 | 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-10-05 | — | — | WO | disclosed |