SCHEMBL5284048

SCHEMBL5284048

CCCCCC1(C(C)(C)C)N=NN=N1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5284371 0.80
SCHEMBL5272722 0.78 TSHR (0.33) TSHRTHRB
SCHEMBL5279540 0.78 TSHR (0.33) TSHRTHRB
SCHEMBL5279541 0.77
SCHEMBL5279175 0.75 TSHR (0.31) TSHRTHRB
SCHEMBL5285420 0.75 CES1 (0.31) TSHRTHRB
SCHEMBL5278284 0.73
SCHEMBL5277353 0.70 TSHR (0.37) TSHRTHRB
SCHEMBL2380894 0.70 FAAH (0.32) TSHRTHRB
SCHEMBL5279412 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed