Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 5/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272722 | 0.89 | TSHR (0.33) | FAAHTSHRTHRBCES1CES2 | |
| SCHEMBL5279541 | 0.74 | — | — | |
| SCHEMBL5273940 | 0.73 | — | — | |
| SCHEMBL5285420 | 0.73 | CES1 (0.31) | FAAHTSHRTHRBCES1CES2 | |
| SCHEMBL20779744 | 0.71 | — | — | |
| SCHEMBL5284048 | 0.70 | TSHR (0.30) | TSHRTHRB | |
| SCHEMBL15701560 | 0.68 | — | — | |
| SCHEMBL5279412 | 0.67 | — | — | |
| SCHEMBL24772486 | 0.67 | FAAH (0.32) | FAAHTSHRTHRBCES1CES2 | |
| Hexane SCHEMBL20877590 | 0.66 | TSHR (0.58) | FAAHTSHRTHRBCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159777-A1 | CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS | CELLMOSAIC INC (US) | 2016-06-09 | — | — | US | claimed |
| US-20120322978-A1 | CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS | CELLMOSAIC, LLC | 2012-12-20 | — | — | US | claimed |
| WO-2011109326-A2 | CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS | HUANG YUMEI (US) | 2011-09-09 | — | — | WO | claimed |
| WO-2013113117-A1 | FLUORINATED PHOSPHONIUM IONIC SALTS LINKED TO CARBENE-PRECURSORS | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2013-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322978-A1 | CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS | STUB1, PFN1, PFDN1 | FAAH 1395/4885TSHR 1485/4885THRB 3325/4885 |
| US-20160159777-A1 | CROSSLINKING REAGENTS, METHODS, AND COMPOSITIONS FOR STUDYING PROTEIN-PROTEIN INTERACTIONS | PBDC1, RCSD1, STUB1 | FAAH 1965/4885TSHR 2243/4885THRB 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.