Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.78 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | NAT1 | P18440 | 1/20 | 0.64 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 1/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284203 | 1.00 | HSD17B3 (0.78) | HSD17B3HSPD1HSPE1NAT1CISD1 | |
| SCHEMBL5284212 | 1.00 | HSD17B3 (0.78) | HSD17B3HSPD1HSPE1NAT1CISD1 | |
| SCHEMBL21301429 | 0.89 | HSD17B3 (0.74) | HSD17B3NAT1CISD1MAOBMAOA | |
| SCHEMBL9331154 | 0.85 | PDE4B (0.73) | HSD17B3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8710472 | 0.85 | HSD17B3 (0.70) | HSD17B3HSPD1HSPE1NAT1CISD1 | |
| SCHEMBL8710470 | 0.85 | HSD17B3 (0.70) | HSD17B3HSPD1HSPE1NAT1CISD1 | |
| SCHEMBL9331160 | 0.85 | PDE4B (0.73) | HSD17B3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17397858 | 0.84 | CISD1 (0.73) | HSD17B3NAT1CISD1MAOBMAOA | |
| SCHEMBL17397856 | 0.84 | CISD1 (0.73) | HSD17B3NAT1CISD1MAOBMAOA | |
| SCHEMBL17397857 | 0.84 | CISD1 (0.73) | HSD17B3NAT1CISD1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-9486447-B2 | Compositions and methods for controlling neuronal excitation | THE GENERAL HOSPITAL CORPORATION (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486447-B2 | Compositions and methods for controlling neuronal excitation | THE GENERAL HOSPITAL CORPORATION (US) | 2016-11-08 | — | — | US | disclosed |
| US-20140330195-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140330195-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-06 | — | — | US | disclosed |
| WO-2012174049-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | THE GENERAL HOSPITAL CORPORATION (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2007002587-A2 | INHIBITORS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN 1 | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330195-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEURONAL EXCITATION | TRPA1, TRPV1, HCN3 | HSD17B3 4403/4885HSPD1 2978/4885HSPE1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.