SCHEMBL5284469

SCHEMBL5284469

Cc1cc(OC(=O)c2c(F)ccc(F)c2F)ccc1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
PLA2G1B P04054 1/20 0.54
ATG4B Q9Y4P1 1/20 0.54
FKBP1A P62942 1/20 0.39
CARM1 Q86X55 1/20 0.39
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5285568 0.80 TDP1 (0.55) TDP1PLA2G1BATG4BFKBP1ACARM1
SCHEMBL5288856 0.78 LMNA (0.47) L3MBTL1
SCHEMBL5297544 0.76 KDM4E (0.38) KMT2AMEN1MAPT
SCHEMBL17355732 0.75 CA1 (0.44) TDP1PLA2G1BATG4BKMT2AL3MBTL1
SCHEMBL3904552 0.75 TDP1 (0.58) TDP1PLA2G1BATG4BFKBP1ACARM1
SCHEMBL11482491 0.73 TDP1 (0.57) TDP1PLA2G1BATG4BFKBP1ACARM1
SCHEMBL9946003 0.72 TDP1 (0.54) TDP1PLA2G1BATG4BFKBP1ACARM1
SCHEMBL17355723 0.71 KMT2A (0.41) TDP1PLA2G1BATG4BKMT2AL3MBTL1
SCHEMBL20439411 0.71 RAB9A (0.56) TDP1PLA2G1BATG4BFKBP1AKMT2A
SCHEMBL26500618 0.70 TDP1 (0.53) TDP1PLA2G1BATG4BFKBP1ACARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007004753-A1 ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES DONGBU HITEK CO., LTD. (KR) 2007-01-11 WO claimed
WO-2007004753-A1 ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES DONGBU HITEK CO., LTD. (KR) 2007-01-11 WO disclosed