Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL528455 | 1.00 | SLC7A5 (0.61) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL12002580 | 0.87 | PNP (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL9732191 | 0.85 | SLC7A5 (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11520041 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL11676367 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL638520 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL1581 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL10978820 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL1580 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM | |
| Tyrosine SCHEMBL11676395 | 0.78 | SLC7A5 (1.00) | SLC7A5ALDH1A1PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598873-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015904-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| US-4212944-A | AEROBICALLY PROPAGATING NOCARDIOPSIS ATRA | PFIZER INC. (US) | 1980-07-15 | — | — | US | disclosed |