Tyrosine

Tyrosine

SCHEMBL9732191

N[C@@H](Cc1ccc(O)cc1)C(=O)O.Nc1ncnc2nc[nH]c12

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.56
PI4KA P42356 2/20 0.51
PI4K2B Q8TCG2 2/20 0.51
PI4K2A Q9BTU6 2/20 0.51
PI4KB Q9UBF8 2/20 0.51
LMNA P02545 1/20 0.51
DRD3 P35462 1/20 0.51
XDH P47989 1/20 0.51
LRRK2 Q5S007 1/20 0.51
PRKACA P17612 1/20 0.42
PRKACG P22612 1/20 0.42
PRKACB P22694 1/20 0.42
AKT2 P31751 1/20 0.42
PTGS1 P23219 2/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
XIAP P98170 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 2/20 0.40
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL528455 0.85 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL528458 0.85 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Dl-Tryptophan SCHEMBL25193338 0.84 KMT2A (0.53) LMNASMN1; SMN2KDM4EADORA3ALOX15
Tyrosine SCHEMBL9732180 0.82 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
Adenine SCHEMBL29522302 0.80 PI4KA (0.59) PI4KAPI4K2BPI4K2API4KBLMNA
Histidine SCHEMBL7197905 0.79 PI4KA (0.51) SLC7A5PI4KAPI4K2BPI4K2API4KB
Tyrosine SCHEMBL12002580 0.79 PNP (0.56) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL528456 0.78 CDC7 (0.50) SLC7A5LMNAPRKACAPRKACGPRKACB
Adenine SCHEMBL1577866 0.78 LMNA (0.56) SLC7A5PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL4201626 0.77 PI4KA (0.55) PI4KAPI4K2BPI4K2API4KBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080306-C Adjusting and controlling factor for expression of nitrile solution deenzyme and gene thereof MITSUBISHI RAYON CO (JP) 2002-03-06 CN disclosed
EP-0332216-B1 NOVEL SUBSTANCE FOR AGRICULTURAL USE AND PROCESS FOR ITS PRODUCTION Kaken Pharmaceutical Co., Ltd. (JP) 1992-11-25 EP disclosed
US-5102794-A Culturing and isolating microorganism KITASATOSPORIA KAKEN PHARMACEUTICAL CO., LTD. (JP) 1992-04-07 US disclosed
US-5032611-A Rice plant disease prevention KAKEN PHARMACEUTICAL CO., LTD. (JP) 1991-07-16 US disclosed
EP-0332216-A1 Novel substance for agricultural use and process for its production Kaken Pharmaceutical Co., Ltd. (JP) 1989-09-13 EP disclosed
US-4784953-A NOCARDIA WHICH FORMS 4(3-PROPIONIC ACID-5-HYDROXY-7-METHYL INDANONE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-11-15 US disclosed