Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278907 | 0.94 | SLC9A1 (0.38) | SLC9A1HCAR3 | |
| SCHEMBL5276607 | 0.91 | GRIA4 (0.33) | SLC9A1 | |
| SCHEMBL5284926 | 0.88 | SLC9A1 (0.34) | SLC9A1GRM2TOP2A | |
| SCHEMBL5278656 | 0.86 | SLC9A1 (0.36) | SLC9A1GRM2TOP2AHCAR3 | |
| SCHEMBL5284372 | 0.85 | SLC9A1 (0.36) | SLC9A1GRM2TOP2AHCAR3 | |
| SCHEMBL5282294 | 0.84 | MAOA (0.31) | — | |
| SCHEMBL5280861 | 0.84 | SLC9A1 (0.39) | SLC9A1GRM2TOP2AHCAR3MAOB | |
| SCHEMBL5278176 | 0.83 | SLC9A1 (0.37) | SLC9A1 | |
| SCHEMBL5277816 | 0.83 | SLC9A1 (0.38) | SLC9A1GRM2TOP2AHCAR3MAOB | |
| SCHEMBL5275006 | 0.83 | SLC9A1 (0.38) | SLC9A1GRM2TOP2AHCAR3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1756107-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006009789-A2 | ARYL-SUBSTITUTED PIPERAZINE DERIVATIVES | NEUROGEN CORPORATION (US) | 2006-01-26 | — | — | WO | disclosed |