Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528214 | 0.93 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL528215 | 0.93 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL526554 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL528312 | 0.86 | KMT2A (0.47) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL528313 | 0.86 | KMT2A (0.47) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL527864 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL527863 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL527992 | 0.85 | GPR139 (0.51) | ALDH1A1KMT2AMEN1HSD17B10L3MBTL1 | |
| SCHEMBL528733 | 0.85 | TSHR (0.53) | ALDH1A1KMT2AMEN1KDM4EGPR139 | |
| SCHEMBL528732 | 0.85 | TSHR (0.53) | ALDH1A1KMT2AMEN1KDM4EGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598493-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014114-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |