SCHEMBL5284761

SCHEMBL5284761

C=CC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.55
MAPT P10636 2/20 0.55
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55
HTT P42858 1/20 0.55
DUSP3 P51452 1/20 0.55
PTPN5 P54829 1/20 0.55
PTPN11 Q06124 1/20 0.55
TSHR P16473 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SPOP O43791 11/20 0.52
ABCC4 O15439 1/20 0.48
CNR1 P21554 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
HPGD P15428 1/20 0.47
APAF1 O14727 2/20 0.43
LMNA P02545 1/20 0.43
APEX1 P27695 1/20 0.43
PLCG1 P19174 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374918 1.00 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL7770365 1.00 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL1131848 1.00 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL1131847 1.00 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL5592457 1.00 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
Hydrochloric Acid SCHEMBL9483729 0.99 TDP1 (0.54) TDP1MAPTPOLBPKMHTT
Hydrochloric Acid SCHEMBL9483725 0.99 TDP1 (0.54) TDP1MAPTPOLBPKMHTT
SCHEMBL1132036 0.88 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL1132035 0.88 TDP1 (0.55) TDP1MAPTPOLBPKMHTT
SCHEMBL1132808 0.88 TDP1 (0.55) TDP1MAPTPOLBPKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118706995-A Analysis method and application of cefdinir intermediate medium control reaction liquid 湖北凌晟药业股份有限公司 2024-09-27 CN claimed
CN-118688349-A Analysis method of cefdinir and cefixime mother nucleus and related impurities 湖北凌晟药业股份有限公司 2024-09-24 CN claimed
CN-117924319-B Method for removing cefixime polymer impurities and method for preparing cefixime 广药白云山化学制药(珠海)有限公司 2024-08-27 CN claimed
CN-117924319-A Method for removing cefixime polymer impurities and method for preparing cefixime 广药白云山化学制药(珠海)有限公司 2024-04-26 CN claimed
CN-113429283-B Method for recovering phenylacetic acid from medical wastewater 湖北凌晟药业有限公司 2022-04-22 CN claimed
WO-2007008672-A1 CRYSTALLINE CEFDINIR TRIHEMIHYDRATE ABBOTT LABORATORIES (US) 2007-01-18 WO claimed
US-20060287289-A1 Crystalline anhydrous cefdinir and crystalline cefdinir hydrates ABBOTT LABORATORIES 2006-12-21 US claimed
US-20060211676-A1 Crystalline anhydrous cefdinir and crystalline cefdinir hydrates ABBOTT LABORATORIES 2006-09-21 US claimed
CN-118706995-A Analysis method and application of cefdinir intermediate medium control reaction liquid 湖北凌晟药业股份有限公司 2024-09-27 CN disclosed
CN-118706995-A Analysis method and application of cefdinir intermediate medium control reaction liquid 湖北凌晟药业股份有限公司 2024-09-27 CN disclosed
CN-118688349-A Analysis method of cefdinir and cefixime mother nucleus and related impurities 湖北凌晟药业股份有限公司 2024-09-24 CN disclosed
CN-118688349-A Analysis method of cefdinir and cefixime mother nucleus and related impurities 湖北凌晟药业股份有限公司 2024-09-24 CN disclosed
CN-117924319-B Method for removing cefixime polymer impurities and method for preparing cefixime 广药白云山化学制药(珠海)有限公司 2024-08-27 CN disclosed
CN-117924319-B Method for removing cefixime polymer impurities and method for preparing cefixime 广药白云山化学制药(珠海)有限公司 2024-08-27 CN disclosed
EP-0854875-B1 NEW CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO (JP) 2001-06-13 EP disclosed
US-6159961-A Cephem compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-12-12 US disclosed
US-5958914-A FOR THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-09-28 US disclosed
EP-0854875-A1 NEW CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
WO-1997012890-A1 NEW CEPHEM COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-04-10 WO disclosed
EP-0280521-A2 Cephalosporin compounds, process for their preparation and pharmaceutical compositions containing them GLAXO GROUP LIMITED (GB) 1988-08-31 EP disclosed