Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SPOP | O43791 | 11/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770365 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL5284761 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1131848 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1131847 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL5592457 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| Hydrochloric Acid SCHEMBL9483729 | 0.99 | TDP1 (0.54) | TDP1MAPTPOLBPKMHTT | |
| Hydrochloric Acid SCHEMBL9483725 | 0.99 | TDP1 (0.54) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132036 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132035 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132808 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2873736-A1 | Chemoenzymatic synthesis of the cephalosporine intermediate 7-amino-3-alkenylcephem-4-carboxylic acid | Sandoz AG (CH) | 2015-05-20 | — | — | EP | disclosed |
| US-8008478-B2 | Process for the preparation of cefixime | LUPIN LIMITED (IN) | 2011-08-30 | — | — | US | disclosed |
| US-8008478-B2 | Process for the preparation of cefixime | LUPIN LIMITED (IN) | 2011-08-30 | — | — | US | disclosed |
| US-7825241-B2 | Cefdinir intermediate | SANDOZ AG (CH) | 2010-11-02 | — | — | US | disclosed |
| US-7825241-B2 | Cefdinir intermediate | SANDOZ AG (CH) | 2010-11-02 | — | — | US | disclosed |
| US-20090227787-A1 | PROCESS FOR THE PREPARATION OF CEFIXIME | LUPIN LIMITED (IN) | 2009-09-10 | — | — | US | disclosed |
| US-20090227787-A1 | PROCESS FOR THE PREPARATION OF CEFIXIME | LUPIN LIMITED (IN) | 2009-09-10 | — | — | US | disclosed |
| US-20080081906-A1 | CEFDINIR INTERMEDIATE | KREMMINGER PETER | 2008-04-03 | — | — | US | disclosed |
| US-20080081906-A1 | CEFDINIR INTERMEDIATE | KREMMINGER PETER | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227787-A1 | PROCESS FOR THE PREPARATION OF CEFIXIME | CYP4F8, CYP3A5, CYP2F1 | TDP1 4577/4885MAPT 4007/4885POLB 2778/4885 |
| US-20080081906-A1 | CEFDINIR INTERMEDIATE | PCMT1, AASDHPPT, SULT1E1 | TDP1 4740/4885MAPT 2866/4885POLB 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.