Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SPOP | O43791 | 11/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374918 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL7770365 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL5284761 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1131848 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL5592457 | 1.00 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| Hydrochloric Acid SCHEMBL9483729 | 0.99 | TDP1 (0.54) | TDP1MAPTPOLBPKMHTT | |
| Hydrochloric Acid SCHEMBL9483725 | 0.99 | TDP1 (0.54) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132036 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132035 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT | |
| SCHEMBL1132808 | 0.88 | TDP1 (0.55) | TDP1MAPTPOLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113308052-B | Sprayable modified polypropylene material and preparation method and application thereof | 万华化学（宁波）有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-113308052-A | Sprayable modified polypropylene material and preparation method and application thereof | 万华化学（宁波）有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-111423148-A | Environment-friendly steam-pressure-free pipe pile water reducing agent and preparation method thereof | 赵良文 | 2020-07-17 | — | — | CN | claimed |
| CN-110845205-A | High-strength environment-friendly antibacterial mortar and preparation method thereof | 湖南辰砾新材料有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-104788471-A | Synthetic method of cefditoren pivoxil mother nucleus | ZHEJIANG HUAFANG PHARMACEUTICAL CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-102020664-B | Synthesis method for cefdinir | UNIV ZHEJIANG TECHNOLOGY | 2012-12-12 | — | — | CN | claimed |
| CN-101974020-B | Method for synthesizing cefdinir | CHINA UNION CHEMPHARMA SUZHOU CO LTD | 2012-09-12 | — | — | CN | claimed |
| CN-102020664-A | Synthesis method for cefdinir | UNIV ZHEJIANG TECHNOLOGY | 2011-04-20 | — | — | CN | claimed |
| CN-101974020-A | Method for synthesizing cefdinir | CHINA UNION CHEMPHARMA SUZHOU CO LTD | 2011-02-16 | — | — | CN | claimed |
| US-7705142-B2 | Process for the preparation of cefixime | HETERO DRUGS LIMITED (IN) | 2010-04-27 | — | — | US | claimed |
| US-20050032771-A1 | Process for the preparation of cefixime via alkyl-or aryl-sulfonates | ANTIBIOTICOS S.P.A. (IT) | 2005-02-10 | — | — | US | claimed |
| EP-1442044-A1 | A PROCESS FOR THE PREPARATION OF CEFIXIME VIA ALKYL-OR ARYL-SULFONATES | Antibioticos S.p.A. (IT) | 2004-08-04 | — | — | EP | claimed |
| EP-0968214-B1 | PURIFICATION PROCESS | BIOCHEMIE GMBH (AT) | 2004-04-07 | — | — | EP | claimed |
| WO-2003040148-A1 | A PROCESS FOR THE PREPARATION OF CEFIXIME VIA ALKYL-OR ARYL-SULFONATES | ANTIBIOTICOS S.P.A. (IT) | 2003-05-15 | — | — | WO | claimed |
| US-6313289-B1 | MAKING CEFIXIME; 7-AMINO-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID AND 2-(AMINOTHIAZOL-4-YL)-2-CARBOXYMETHOXYIMINO)ACETIC ACID ESTER ARE REACTED; BY-PRODUCT INHIBITION; SALT FORMATION, AMINATION | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2001-11-06 | — | — | US | claimed |
| EP-0968214-A1 | PURIFICATION PROCESS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-01-05 | — | — | EP | claimed |
| EP-0763043-B1 | PROCESS FOR THE PREPARATION OF TRIHYDRATED CEFIXIME | MARCHAM TRADING & INVESTMENT L (IE) | 1998-09-23 | — | — | EP | claimed |
| WO-1998031685-A1 | PURIFICATION PROCESS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1998-07-23 | — | — | WO | claimed |
| EP-0763043-A1 | PROCESS FOR THE PREPARATION OF TRIHYDRATED CEFIXIME | MARCHAM TRADING & INVESTMENT LTD. (IE) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033753-A1 | PROCESS FOR THE PREPARATION OF TRIHYDRATED CEFIXIME | MARCHAM TRADING & INVESTMENT LTD. (IE) | 1995-12-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032771-A1 | Process for the preparation of cefixime via alkyl-or aryl-sulfonates | CYP4X1, SULT1E1, SULT2A1 | TDP1 4871/4885MAPT 4452/4885POLB 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.