SCHEMBL5284812

SCHEMBL5284812

Cc1ccc(OCCOc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
DRD2 P14416 4/20 0.50
DRD4 P21917 4/20 0.50
DRD3 P35462 4/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
MAOB P27338 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824702 0.91 KMT2A (0.59) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL14579974 0.85 MEN1 (0.62) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL10593412 0.85 MEN1 (0.62) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL313373 0.84 DRD2 (0.64) MEN1KMT2ADRD2DRD4DRD3
SCHEMBL15472274 0.84 FFAR4 (0.48) MEN1KMT2ADRD2DRD4DRD3
SCHEMBL3764814 0.83 KCNA3 (0.54) MEN1KMT2ALMNAALDH1A1RXRA
SCHEMBL801701 0.83 MEN1 (0.53) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL13568875 0.83 MEN1 (0.61) MEN1KMT2ALMNAHTTSMN1; SMN2
SCHEMBL9946032 0.82 RXRA (0.64) KMT2ASMN1; SMN2L3MBTL1MAOBALDH1A1
SCHEMBL9946062 0.82 RXRA (0.64) KMT2ASMN1; SMN2L3MBTL1MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed