Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 8/20 | 0.59 |
| ▸ | CA12 | O43570 | 7/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.59 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.59 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267917 | 0.92 | MAPK1 (0.71) | MAPK1CA9CA12CA2RAB9A | |
| SCHEMBL16558061 | 0.91 | MAPK1 (0.58) | MAPK1CA9CA12CA2RAB9A | |
| SCHEMBL11802279 | 0.90 | MAPK1 (0.71) | MAPK1KEAP1GAANFE2L2 | |
| SCHEMBL8606028 | 0.87 | CA9 (0.60) | MAPK1CA9CA12CA2RAB9A | |
| SCHEMBL5285705 | 0.86 | MAPK1 (0.63) | MAPK1SMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL2057514 | 0.86 | CA9 (0.66) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL11598927 | 0.82 | TDP1 (0.58) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL7230825 | 0.81 | CA9 (0.61) | CA9CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL16558052 | 0.81 | MAPK1 (0.51) | MAPK1CA9CA12CA2RAB9A | |
| SCHEMBL13898757 | 0.80 | CA9 (0.56) | MAPK1CA9CA12CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150071918-A1 | PEPTIDES FOR THE TREATMENT OF CANCER | UNIVERSITY OF SOUTH FLORIDA | 2015-03-12 | — | — | US | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | MAPK1 3183/4885CA9 1224/4885CA12 2695/4885 |
| US-20150071918-A1 | PEPTIDES FOR THE TREATMENT OF CANCER | CD44, PTK2, SDC1 | MAPK1 194/4885CA9 1597/4885CA12 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.