Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27617461 | 1.00 | PRMT3 (0.58) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL21847053 | 0.82 | PRMT3 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Acetic Acid SCHEMBL14782437 | 0.82 | PRMT3 (0.70) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL6246084 | 0.80 | CYP2C9 (0.38) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL21816631 | 0.80 | ALDH1A1 (0.38) | MAPK1ALDH1A1CCR2 | |
| Trifluoroacetic Acid SCHEMBL9069011 | 0.78 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL48539 | 0.76 | — | — | |
| Trifluoroacetic Acid SCHEMBL13724288 | 0.76 | KDM4A (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL21816723 | 0.76 | KDM4A (0.35) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Trifluoroacetic Acid SCHEMBL27829960 | 0.76 | CA14 (0.44) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807403-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006046030-A2 | TETRACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-05-04 | — | — | WO | disclosed |