Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302093 | 0.93 | GSK3A (0.41) | GSK3AGSK3BALOX15MEN1KMT2A | |
| SCHEMBL5301204 | 0.83 | KMT2A (0.49) | ALOX15MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2294482 | 0.78 | NAMPT (0.48) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5295936 | 0.77 | MAPT (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2292264 | 0.77 | NPC1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2295362 | 0.77 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5302367 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5287647 | 0.76 | KMT2A (0.49) | ALOX15MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2292578 | 0.76 | KDM4E (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2294478 | 0.76 | NPC1 (0.48) | MEN1KMT2ASMN1; SMN2HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828144-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006053342-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | claimed |