Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLD1 | P28340 | 1/20 | 0.57 |
| ▸ | TK1 | P04183 | 5/20 | 0.51 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487624 | 0.90 | POLB (0.45) | POLBPOLA1POLD1TK1 | |
| SCHEMBL8088403 | 0.90 | POLB (0.60) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL5191075 | 0.89 | POLB (0.59) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL2384264 | 0.88 | POLB (0.62) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL9621370 | 0.88 | TK1 (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL18790013 | 0.87 | POLB (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL427926 | 0.87 | POLB (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL15343781 | 0.87 | POLB (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL2148399 | 0.87 | POLB (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL21437348 | 0.86 | POLB (0.61) | POLBPOLA1POLD1TK1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053702-A2 | SYNTHESIS OF FOUR COLOR 3'-O-ALLYL MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007002204-A2 | PYROSEQUENCING METHODS AND RELATED COMPOSTIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-01-04 | — | — | WO | disclosed |