Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.60 |
| ▸ | POLD1 | P28340 | 1/20 | 0.60 |
| ▸ | TK1 | P04183 | 6/20 | 0.55 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191075 | 0.92 | POLB (0.59) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL2384264 | 0.91 | POLB (0.62) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL9621370 | 0.91 | TK1 (0.67) | POLBPOLA1POLD1TK1 | |
| SCHEMBL5285299 | 0.90 | POLB (0.57) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL21437348 | 0.89 | POLB (0.61) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL6534888 | 0.89 | POLB (0.61) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL9562911 | 0.89 | POLB (0.69) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL5188691 | 0.87 | POLB (0.54) | POLBPOLA1POLD1TK1RNASE1 | |
| SCHEMBL23934882 | 0.86 | POLB (0.71) | POLBPOLA1POLD1TK1 | |
| SCHEMBL21902546 | 0.86 | TK1 (0.56) | POLBPOLA1POLD1TK1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866796-B1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2000-11-29 | — | — | EP | claimed |
| EP-0866796-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1998-09-30 | — | — | EP | claimed |
| WO-1997011083-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1997-03-27 | — | — | WO | claimed |
| EP-0866796-B1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2000-11-29 | — | — | EP | disclosed |
| EP-0866796-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997011083-A1 | IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS | MEDICAL RESEARCH COUNCIL (GB) | 1997-03-27 | — | — | WO | disclosed |