SCHEMBL5285370

SCHEMBL5285370

CCCCc1c(C)nnn1CCC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 5/20 0.37
GRIA4 P48058 1/20 0.36
MAOB P27338 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GRM2 Q14416 2/20 0.33
CYP1A2 P05177 2/20 0.33
HSD11B1 P28845 1/20 0.33
TOP2A P11388 1/20 0.32
GABRB3 P28472 1/20 0.31
HCAR3 P49019 1/20 0.30
MEN1 O00255 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280259 0.92 SLC9A1 (0.42) SLC9A1GRIA4MAOBALDH1A1GRM2
SCHEMBL5280965 0.89 SLC9A1 (0.45) SLC9A1MAOBALDH1A1GRM2HCAR3
SCHEMBL5279133 0.88 SLC9A1 (0.39) SLC9A1GRIA4ADORA2AADORA2BALDH1A1
SCHEMBL5279076 0.86 MAOB (0.33) SLC9A1GRIA4MAOBHSD11B1GABRB3
SCHEMBL5277904 0.85 SLC9A1 (0.42) SLC9A1GRIA4ALDH1A1GRM2HSD11B1
SCHEMBL5275678 0.82 SLC9A1 (0.40) SLC9A1GRIA4ADORA2AADORA2BALDH1A1
SCHEMBL5279279 0.81 SLC9A1 (0.45) SLC9A1ALDH1A1GRM2GABRB3HCAR3
SCHEMBL5282446 0.81 MAOB (0.41) SLC9A1GRIA4MAOBALDH1A1GRM2
SCHEMBL5280768 0.80 MAOB (0.46) SLC9A1MAOBALDH1A1HSD11B1GABRB3
SCHEMBL5283666 0.79 GRM2 (0.39) SLC9A1GRIA4MAOBADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed