Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177345 | 0.94 | MAOB (0.42) | MAOBHSD11B1GABRB3SLC9A1ALDH1A1 | |
| SCHEMBL5272831 | 0.87 | GABRB3 (0.41) | MAOBGABRB3KDM4EALOX15MAPK1 | |
| SCHEMBL5280259 | 0.80 | SLC9A1 (0.42) | MAOBHSD11B1GABRB3TSHRSLC9A1 | |
| SCHEMBL5285370 | 0.80 | SLC9A1 (0.37) | MAOBHSD11B1GABRB3SLC9A1ALDH1A1 | |
| SCHEMBL5275440 | 0.79 | MAOB (0.58) | MAOBHSD11B1SLC9A1ALDH1A1 | |
| SCHEMBL5273564 | 0.78 | — | — | |
| SCHEMBL5277438 | 0.78 | MAOB (0.56) | MAOBHSD11B1GABRB3 | |
| SCHEMBL5281133 | 0.78 | MAOB (0.45) | MAOBHSD11B1 | |
| SCHEMBL5279076 | 0.78 | MAOB (0.33) | MAOBHSD11B1GABRB3SLC9A1 | |
| SCHEMBL5278875 | 0.78 | MAOB (0.45) | MAOBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |