Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529284 | 0.91 | ALDH1A1 (0.56) | MAPTKMT2ALMNAALDH1A1HPGD | |
| SCHEMBL529245 | 0.90 | MEN1 (0.52) | MAPTMEN1KMT2AHSD17B10RXFP1 | |
| SCHEMBL528369 | 0.90 | MEN1 (0.52) | MAPTMEN1KMT2AHSD17B10RXFP1 | |
| SCHEMBL528702 | 0.88 | MAPT (0.58) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL528349 | 0.88 | RXFP1 (0.49) | MAPTMEN1KMT2AHSD17B10RXFP1 | |
| SCHEMBL527894 | 0.88 | RXFP1 (0.49) | MAPTMEN1KMT2AHSD17B10RXFP1 | |
| SCHEMBL528572 | 0.86 | RXFP1 (0.48) | MAPTMEN1KMT2AHSD17B10RXFP1 | |
| SCHEMBL529051 | 0.85 | MAPT (0.71) | MAPTMEN1KMT2ARAB9ALMNA | |
| SCHEMBL529639 | 0.85 | MAPT (0.55) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL528851 | 0.85 | RXFP1 (0.46) | MAPTMEN1KMT2AHSD17B10RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |