Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528274 | 0.91 | L3MBTL1 (0.47) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL529245 | 0.88 | MEN1 (0.52) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL528369 | 0.88 | MEN1 (0.52) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL529438 | 0.87 | MAPT (0.54) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL528349 | 0.86 | RXFP1 (0.49) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL527894 | 0.86 | RXFP1 (0.49) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL528613 | 0.86 | MAPT (0.54) | RXFP1HSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL529361 | 0.84 | ALDH1A1 (0.50) | MEN1KMT2ARAB9AMRGPRX1TSPO | |
| SCHEMBL528272 | 0.81 | MAPT (0.45) | RXFP1MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL528851 | 0.80 | RXFP1 (0.46) | RXFP1HSD17B10MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |