⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1313598 | 0.93 | ALDH1A1 (0.46) | — | |
| SCHEMBL6984030 | 0.91 | ALDH1A1 (0.50) | — | |
| SCHEMBL6984192 | 0.91 | ALDH1A1 (0.50) | — | |
| SCHEMBL222319 | 0.84 | — | — | |
| SCHEMBL9601938 | 0.79 | KDM5A (0.37) | — | |
| SCHEMBL15484733 | 0.77 | — | — | |
| SCHEMBL1306752 | 0.76 | PAOX (0.43) | — | |
| SCHEMBL15485092 | 0.75 | — | — | |
| SCHEMBL3164933 | 0.75 | — | — | |
| SCHEMBL5259256 | 0.75 | KDM5A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| EP-2597955-B1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE INC (JP) | 2016-01-20 | — | — | EP | claimed |
| US-20150307486-A1 | ERGOLINE DERIVATIVES AS DOPAMINE RECEPTOR MODULATORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-10-29 | — | — | US | claimed |
| US-9120749-B2 | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2015-09-01 | — | — | US | claimed |
| CN-101970394-B | Novel cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA AS | 2015-05-27 | — | — | CN | claimed |
| US-8853193-B2 | Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-07 | — | — | US | claimed |
| US-8735584-B2 | Protein kinase inhibitors and use thereof | MERCK PATENT GMBH (DE) | 2014-05-27 | — | — | US | claimed |
| WO-2014078857-A1 | ERGOLINE DERIVATIVES AS DOPAMINE RECEPTOR MODULATORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-05-22 | — | — | WO | claimed |
| US-20130217671-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2013-08-22 | — | — | US | claimed |
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | claimed |
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | claimed |
| US-5585497-A | USEFUL IN TREATMENT OF NEUROPSYCHIATRIC DISORDERS, ESPECIALLY THOSE ASSOCIATED WITH A DYSFUNCTION OF THE DOPAMINERGIC SYSTEMS | SANOFI (FR) | 1996-12-17 | — | — | US | claimed |
| US-5502059-A | DOPAMINERGIC DYSFUNCTION DISORDERS | SANOFI (FR) | 1996-03-26 | — | — | US | claimed |
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | claimed |
| EP-0055099-B1 | PENICILLIN DERIVATIVES | ICI PHARMA (FR) | 1984-10-24 | — | — | EP | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| EP-0055099-A1 | Penicillin derivatives | ICI PHARMA (FR) | 1982-06-30 | — | — | EP | claimed |