Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | GNA15 | P30679 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587088 | 0.91 | FFAR1 (0.59) | FFAR1FFAR4LMNAL3MBTL1F2RL1 | |
| SCHEMBL4654749 | 0.90 | FFAR1 (0.70) | FFAR1SRD5A2FFAR4F2RL1TDP1 | |
| Apteniol A SCHEMBL16431559 | 0.88 | FFAR1 (0.89) | FFAR1SRD5A2FFAR4LMNAL3MBTL1 | |
| SCHEMBL5927538 | 0.86 | FFAR1 (0.64) | FFAR1SRD5A2FFAR4 | |
| SCHEMBL7824247 | 0.85 | FFAR1 (0.54) | FFAR1LMNAL3MBTL1 | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL8767620 | 0.85 | FFAR1 (0.54) | FFAR1FFAR4LMNAL3MBTL1 | |
| Methyl 3-Phenylpropanoate SCHEMBL213543 | 0.84 | KEAP1 (0.70) | FFAR1FFAR4LMNATDP1 | |
| SCHEMBL22922181 | 0.84 | CYP4F2 (0.59) | LMNAF2RL1ADRB2ADRB1TDP1 | |
| Methyl 3-Phenylpropanoate SCHEMBL27506579 | 0.83 | KEAP1 (0.68) | FFAR1FFAR4LMNATDP1 | |
| Methyl 3-Phenylpropanoate SCHEMBL6734679 | 0.83 | KEAP1 (0.68) | FFAR1FFAR4LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005774-A9 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | BEXEL PHARMACEUTICALS INC (US) | 2007-03-08 | — | — | WO | disclosed |