Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PCNA | P12004 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL8402039 | 0.95 | FFAR1 (0.61) | FFAR1KEAP1FFAR4LMNAESRRB | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL95254 | 0.93 | HDAC2 (0.53) | ESR1ESR2LMNAMEN1KMT2A | |
| SCHEMBL1587088 | 0.93 | FFAR1 (0.59) | FFAR1KEAP1FFAR4LMNAL3MBTL1 | |
| 4-Hydroxyhydrocinnamic Acid Methyl Ester SCHEMBL30611554 | 0.91 | HDAC2 (0.51) | ESR1ESR2LMNAMEN1KMT2A | |
| SCHEMBL7824247 | 0.86 | FFAR1 (0.54) | FFAR1KEAP1LMNAL3MBTL1 | |
| Methyl 3-Phenylpropanoate SCHEMBL213543 | 0.86 | KEAP1 (0.70) | FFAR1KEAP1FFAR4LMNAHDAC2 | |
| Hydroxyphenyl Propionic Acid SCHEMBL28123368 | 0.85 | FFAR1 (0.63) | FFAR1KEAP1FFAR4ESR1ESR2 | |
| Hydroxyphenyl Propionic Acid SCHEMBL35486 | 0.85 | FFAR1 (0.68) | FFAR1KEAP1FFAR4ESR1ESR2 | |
| SCHEMBL22922181 | 0.85 | CYP4F2 (0.59) | LMNAKMT2AALDH1A1 | |
| SCHEMBL3469156 | 0.85 | MAPT (0.50) | ESR1ESR2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |