SCHEMBL5286915

SCHEMBL5286915

CON=C1CN(c2c(F)cc(N3C[C@@H](N(C)C(=O)O)OC3=O)cc2F)C1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.41
MAOB P27338 5/20 0.31
CALML3 P27482 4/20 0.31
LMNA P02545 1/20 0.31
PTGS1 P23219 1/20 0.31
SDHA P31040 1/20 0.31
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326371 0.89 MAOA (0.43) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5325916 0.87 MAOA (0.38) MAOA
SCHEMBL5329983 0.84 MAOA (0.44) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5328160 0.82 MAOA (0.47) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5323611 0.82 MAOA (0.47) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5286908 0.82 MAOA (0.46) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5727240 0.80 MAOA (0.49) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5326903 0.79 MAOA (0.42) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL17975529 0.79 MAOA (0.48) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5285156 0.78 MAOA (0.55) MAOAMAOBCALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007004049-A1 OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-11 WO claimed
WO-2007004049-A1 OXAZOLIDINONES CONTAINING AZETIDINE AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-01-11 WO disclosed