Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528222 | 0.93 | MAPT (0.66) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528500 | 0.91 | MAPT (0.77) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528121 | 0.90 | MAPT (0.75) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL527892 | 0.89 | MAPT (0.73) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528849 | 0.88 | MAPT (0.73) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528837 | 0.87 | MAPT (0.72) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528826 | 0.87 | MAPT (0.64) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528800 | 0.86 | MAPT (0.62) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528007 | 0.86 | MAPT (0.62) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL530943 | 0.85 | MAPT (0.57) | MAPTHTTKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |