Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529049 | 0.90 | MAPT (0.57) | MAPTHTTGAATP53SMN1; SMN2 | |
| SCHEMBL529695 | 0.88 | MAPT (0.50) | MAPTHTTGAATP53SMN1; SMN2 | |
| SCHEMBL528717 | 0.85 | MAPT (0.76) | MAPTHTTGAATP53SMN1; SMN2 | |
| SCHEMBL530471 | 0.81 | MAPT (0.56) | MAPTGAATP53SMN1; SMN2LMNA | |
| SCHEMBL531180 | 0.80 | KMT2A (0.61) | MAPTGAATP53SMN1; SMN2LMNA | |
| SCHEMBL528222 | 0.79 | MAPT (0.66) | MAPTHTTGAASMN1; SMN2LMNA | |
| SCHEMBL528500 | 0.77 | MAPT (0.77) | MAPTHTTGAASMN1; SMN2LMNA | |
| SCHEMBL528121 | 0.76 | MAPT (0.75) | MAPTHTTGAASMN1; SMN2LMNA | |
| SCHEMBL527915 | 0.75 | ALDH1A1 (0.59) | MAPTHTTGAATP53SMN1; SMN2 | |
| SCHEMBL528849 | 0.74 | MAPT (0.73) | MAPTHTTGAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |