Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529256 | 0.91 | MAPT (0.66) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528717 | 0.91 | MAPT (0.76) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528121 | 0.91 | MAPT (0.75) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528383 | 0.90 | NPSR1 (0.65) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528488 | 0.90 | MAPT (0.64) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL527892 | 0.89 | MAPT (0.73) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528300 | 0.89 | MAPT (0.63) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528849 | 0.89 | MAPT (0.73) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528277 | 0.88 | MAPT (0.62) | MAPTHTTGAALMNAALDH1A1 | |
| SCHEMBL528294 | 0.88 | KDM4E (0.65) | MAPTHTTGAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |