Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14061880 | 0.91 | DGAT1 (0.56) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL14061958 | 0.88 | DGAT1 (0.47) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL14137097 | 0.88 | DGAT1 (0.49) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL3045910 | 0.83 | SMN1; SMN2 (0.45) | DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL14061904 | 0.82 | DGAT1 (0.47) | DGAT1SMN1; SMN2 | |
| SCHEMBL14137103 | 0.82 | DGAT1 (0.58) | DGAT1SMN1; SMN2 | |
| SCHEMBL629696 | 0.81 | SMN1; SMN2 (0.58) | DGAT1DRD2SMN1; SMN2 | |
| SCHEMBL14137122 | 0.81 | DGAT1 (0.50) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL15691860 | 0.81 | DGAT1 (0.50) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 | |
| SCHEMBL14061941 | 0.79 | DGAT1 (0.41) | DGAT1DRD2HTR1DDRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |