SCHEMBL5287502

SCHEMBL5287502

Cc1ccc(OCCOc2ccc(C(C)(C)C)cc2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.55
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 2/20 0.49
RECQL P46063 1/20 0.48
HTR1A P08908 1/20 0.46
L3MBTL1 Q9Y468 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
KMT2A Q03164 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
S1PR4 O95977 1/20 0.44
MAPT P10636 3/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPK1 P28482 2/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8715466 0.88 KDM4E (0.51) KDM4ESMN1; SMN2ALDH1A1RECQLHTR1A
SCHEMBL5279217 0.88 TDP1 (0.50) KDM4ESMN1; SMN2ALDH1A1L3MBTL1MAPT
SCHEMBL5292022 0.87 SMN1; SMN2 (0.53) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL5282382 0.83 TSHR (0.62) KDM4ESMN1; SMN2L3MBTL1NPC1RAB9A
SCHEMBL9808196 0.82 HPGD (0.58) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL891407 0.81 SMN1; SMN2 (0.61) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL3806966 0.81 TDP1 (0.56) KDM4ESMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL5286863 0.80 L3MBTL1 (0.55) KDM4ESMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL12889980 0.79 MRGPRX4 (0.52) KDM4ERECQLL3MBTL1RAB9ATSHR
SCHEMBL5293729 0.79 SMN1; SMN2 (0.47) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed