SCHEMBL8715466

SCHEMBL8715466

Cc1ccc(OCCOc2cc(C(C)(C)C)cc(C(C)(C)C)c2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.51
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HTR1A P08908 1/20 0.46
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 5/20 0.44
KMT2A Q03164 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
S1PR4 O95977 1/20 0.44
MAPT P10636 3/20 0.43
HPGD P15428 4/20 0.43
MAPK1 P28482 3/20 0.43
MEN1 O00255 2/20 0.43
POLB P06746 2/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5287502 0.88 KDM4E (0.55) KDM4ESMN1; SMN2ALDH1A1HTR1ARECQL
SCHEMBL891407 0.81 SMN1; SMN2 (0.61) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL5292022 0.80 SMN1; SMN2 (0.53) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL5286863 0.77 L3MBTL1 (0.55) KDM4ESMN1; SMN2ALDH1A1L3MBTL1KMT2A
SCHEMBL8640378 0.76 HTR1A (0.63) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL9808196 0.76 HPGD (0.58) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL5283280 0.76 KMT2A (0.57) KDM4ESMN1; SMN2ALDH1A1L3MBTL1KMT2A
SCHEMBL9011867 0.75 SMN1; SMN2 (0.59) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1
SCHEMBL5279217 0.75 TDP1 (0.50) KDM4ESMN1; SMN2ALDH1A1L3MBTL1MAPT
SCHEMBL15085872 0.75 SMN1; SMN2 (0.51) KDM4ESMN1; SMN2ALDH1A1HTR1AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851951-A Heat sensitive recording material OJI PAPER CO., LTD. (JP) 1998-12-22 US disclosed
EP-0792754-A2 Heat sensitive recording material Oji Paper Co., Ltd. (JP) 1997-09-03 EP disclosed