SCHEMBL5287575

SCHEMBL5287575

CCCCc1c(Cl)nnn1C

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.45
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279739 0.88 MAOB (0.34) MAOBGABRA2GABRB2
SCHEMBL5278335 0.81 SLC9A1 (0.36) MAOBGABRA2GABRB2
SCHEMBL5279578 0.81 SLC9A1 (0.41) MAOBGABRA2GABRB2
SCHEMBL5284779 0.79
SCHEMBL5275132 0.78 MAOB (0.32) MAOBGABRA2GABRB2
SCHEMBL5273367 0.78 SLC9A1 (0.44) MAOB
SCHEMBL5275440 0.78 MAOB (0.58) MAOBHSD11B1
SCHEMBL5280768 0.78 MAOB (0.46) MAOBHSD11B1
SCHEMBL5278875 0.76 MAOB (0.45) MAOBHSD11B1
SCHEMBL5277438 0.76 MAOB (0.56) MAOBGABRA2GABRB2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed