Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968128 | 0.86 | EGLN1 (0.52) | EGLN1THRATHRB | |
| SCHEMBL965197 | 0.85 | EGLN1 (0.57) | EGLN1EGLN2 | |
| SCHEMBL965528 | 0.81 | EGLN1 (0.52) | EGLN1THRATHRB | |
| SCHEMBL967008 | 0.79 | EGLN1 (0.56) | EGLN1EGLN2 | |
| SCHEMBL1973337 | 0.78 | EGLN1 (0.46) | EGLN1EGLN2THRATHRB | |
| SCHEMBL967496 | 0.75 | EGLN1 (0.56) | EGLN1EGLN2 | |
| SCHEMBL966893 | 0.73 | EGLN1 (0.57) | EGLN1 | |
| SCHEMBL966104 | 0.71 | EGLN1 (0.56) | EGLN1EGLN2 | |
| SCHEMBL1974908 | 0.71 | EGLN1 (0.49) | EGLN1EGLN2 | |
| SCHEMBL3401638 | 0.70 | EGLN1 (0.57) | EGLN1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866318-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006094292-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2006-09-08 | — | — | WO | disclosed |