Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL528776

N.Nc1ccc(C=Cc2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
CYP19A1 P11511 2/20 0.44
MAOA P21397 2/20 0.44
NFE2L2 Q16236 3/20 0.40
TRPA1 O75762 2/20 0.40
DHFR P00374 2/20 0.40
GRM4 Q14833 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
POLB P06746 1/20 0.35
PELI1 Q96FA3 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2569625 0.98 MAOB (0.45) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL11681169 0.90 CYP19A1 (0.55) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL27835064 0.90 CYP19A1 (0.55) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL28035372 0.87 ALDH1A1 (0.39) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL5568778 0.87 NFE2L2 (0.42) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL27661664 0.81 ALDH1A1 (0.44) MAOAALDH1A1MEN1KMT2AHPGD
SCHEMBL5572156 0.78 PELI1 (0.44) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL872533 0.76 NFE2L2 (0.38) MAOBCYP19A1MAOANFE2L2TRPA1
SCHEMBL11848111 0.76 CA1 (0.47) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL27932668 0.76 ALDH1A1 (0.39) MAOANFE2L2DHFRALDH1A1PELI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012014758-A1 LIGHT-EMITTING DEVICE AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2010004944-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-14 WO disclosed