SCHEMBL5287799

SCHEMBL5287799

CC/C=C\C=COC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 3/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PPARA Q07869 1/20 0.34
OXER1 Q8TDS5 3/20 0.32
GLO1 Q04760 1/20 0.31
FFAR1 O14842 1/20 0.30
MAPT P10636 1/20 0.30
CYP19A1 P11511 1/20 0.30
RXRA P19793 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10856443 1.00 TRPA1 (0.40) TRPA1ALDH1A1LMNAHSD17B10PPARA
SCHEMBL5287805 1.00 TRPA1 (0.40) TRPA1ALDH1A1LMNAHSD17B10PPARA
SCHEMBL2375960 0.85
SCHEMBL30038 0.85
SCHEMBL4531307 0.84 ALDH1A1 (0.39) TRPA1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL4531306 0.84 ALDH1A1 (0.39) TRPA1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL4218417 0.84 FASN (0.41) ALDH1A1LMNAHSD17B10PPARAOXER1
SCHEMBL4218413 0.84 FASN (0.41) ALDH1A1LMNAHSD17B10PPARAOXER1
SCHEMBL4218411 0.84 FASN (0.41) ALDH1A1LMNAHSD17B10PPARAOXER1
Fluoride SCHEMBL134341 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007003346-A2 FUNGICIDAL AGENTS MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2007-01-11 WO disclosed