SCHEMBL5287971

SCHEMBL5287971

[CH2]CS(=O)(=O)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.63
CA2 P00918 3/20 0.63
CA7 P43166 2/20 0.63
CA14 Q9ULX7 2/20 0.63
CA1 P00915 2/20 0.59
KEAP1 Q14145 1/20 0.57
ALDH1A1 P00352 3/20 0.56
CA9 Q16790 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16477917 0.83 CA12 (0.68) CA12CA2CA7CA14CA1
SCHEMBL813026 0.83 CA2 (0.68) CA12CA2CA7CA14CA1
SCHEMBL6534021 0.83 CA12 (0.68) CA12CA2CA7CA14CA1
SCHEMBL2112943 0.81 CA2 (0.65) CA12CA2CA7CA14CA1
SCHEMBL4901848 0.79 CA2 (0.64) CA12CA2CA7CA14CA1
SCHEMBL1706621 0.78 CA2 (0.68) CA12CA2CA7CA14CA1
SCHEMBL6055917 0.78 CA12 (0.52) CA12CA2CA7CA14CA1
Benzyl(Benzylsulfamoyl)Amine SCHEMBL2298224 0.78 CA12 (1.00) CA12CA2CA7CA14CA1
SCHEMBL24990593 0.76 CA12 (0.59) CA12CA2CA7CA14CA1
SCHEMBL11690253 0.76 CA12 (0.59) CA12CA2CA7CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070032522-A1 Antiviral agents VIROBAY, INC. 2007-02-08 US disclosed
WO-2007005779-A2 ANTIVIRAL AGENTS VIROBAY, INC. (US) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032522-A1 Antiviral agents MAVS, HAVCR2, EIF2AK2 CA12 4464/4885CA2 4345/4885CA7 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.