Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19304523 | 0.90 | HPRT1 (0.61) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL9167757 | 0.85 | HPRT1 (0.65) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL12746417 | 0.85 | HPRT1 (0.61) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL9170861 | 0.83 | HPRT1 (0.60) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL9169415 | 0.82 | HPRT1 (0.59) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL9172797 | 0.82 | HPRT1 (0.59) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL28867905 | 0.80 | MMP8 (0.57) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL4765072 | 0.78 | MMP8 (0.59) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL8966036 | 0.78 | MMP8 (0.59) | HPRT1MMP8TP53ELANEEPHX2 | |
| SCHEMBL15343891 | 0.78 | MMP8 (0.59) | HPRT1MMP8TP53ELANEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008848-A2 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE CARBOXY MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |