Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.65 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746417 | 0.91 | HPRT1 (0.61) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL19304523 | 0.88 | HPRT1 (0.61) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL9170861 | 0.87 | HPRT1 (0.60) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL9169415 | 0.86 | HPRT1 (0.59) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL9172797 | 0.86 | HPRT1 (0.59) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL5288742 | 0.85 | HPRT1 (0.61) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL29505147 | 0.82 | HPRT1 (0.58) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL8966036 | 0.81 | MMP8 (0.59) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL4765072 | 0.81 | MMP8 (0.59) | HPRT1MMP8ELANETP53EPHX2 | |
| SCHEMBL15343891 | 0.81 | MMP8 (0.59) | HPRT1MMP8ELANETP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650360-A1 | PHOSPHONO DERIVATIVES AS ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | THE UPJOHN COMPANY (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994002152-A2 | PHOSPHONO DERIVATIVES AS ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | THE UPJOHN COMPANY (US) | 1994-02-03 | — | — | WO | disclosed |