Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778906 | 1.00 | RRM1 (0.33) | RRM1S1PR2S1PR1S1PR3S1PR5 | |
| Trifluoroacetic Acid SCHEMBL8921705 | 0.93 | S1PR1 (0.40) | S1PR2S1PR1S1PR3S1PR5 | |
| Trifluoroacetic Acid SCHEMBL8919870 | 0.93 | S1PR1 (0.40) | S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL9017360 | 0.87 | GRIA1 (0.41) | GNAI3GNAO1GNAI1GRIA1CHRNB2 | |
| SCHEMBL8778928 | 0.87 | RRM1 (0.35) | RRM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL528796 | 0.87 | RRM1 (0.35) | RRM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL526872 | 0.87 | GRIA1 (0.41) | GNAI3GNAO1GNAI1GRIA1CHRNB2 | |
| SCHEMBL526843 | 0.86 | RRM1 (0.35) | RRM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL8778929 | 0.86 | RRM1 (0.35) | RRM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL527539 | 0.85 | DPP7 (0.34) | RRM1DPP7GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190278-A1 | Compounds for the Treatment/Prevention of Ocular Inflammatory Diseases | LABORATOIRES FOURNIER SA (FR) | 2013-07-25 | — | — | US | disclosed |
| EP-2598131-A1 | COMPOUNDS FOR THE TREATMENT/PREVENTION OF OCULAR INFLAMMATORY DISEASES | Laboratoires Fournier S.A. (FR) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013884-A1 | COMPOUNDS FOR THE TREATMENT/PREVENTION OF OCULAR INFLAMMATORY DISEASES | LABORATOIRES FOURNIER SA (FR) | 2012-02-02 | — | — | WO | disclosed |
| EP-0669316-B1 | Analogs of 15-deoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER IND & SANTE (FR) | 1997-07-30 | — | — | EP | disclosed |
| EP-0669316-A1 | Analogs of 15-déoxyspergualine, process for their preparation and their use as immunosuppressive agents | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190278-A1 | Compounds for the Treatment/Prevention of Ocular Inflammatory Diseases | TNF, NFKBIA, ALDH1A2 | RRM1 3467/4885S1PR2 408/4885S1PR1 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.