Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389429 | 0.79 | GRIA1 (0.39) | PTPRAMAPTGRIA1GRIA2GRIA4 | |
| SCHEMBL7454145 | 0.75 | SLC7A5 (0.45) | PTPRAGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL4575373 | 0.74 | MAPT (0.37) | MAPTCYP2C19ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10420573 | 0.70 | MAPT (0.35) | MAPTALDH1A1KMT2A | |
| SCHEMBL16324473 | 0.68 | L3MBTL1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL9912464 | 0.68 | PTPRA (0.48) | PTPRAMAPTGRIA1GRIA2GRIA4 | |
| SCHEMBL13957603 | 0.66 | GRIA1 (0.46) | MAPTGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL5289522 | 0.66 | CYP2C19 (0.49) | MAPTGRIA1GRIA2GRIA4GRIA3 | |
| SCHEMBL3194686 | 0.66 | SLC7A5 (0.49) | PTPRAGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL3194682 | 0.66 | PTPRA (0.46) | PTPRAMAPTGRIA1GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002469-A2 | THERAPEUTIC COMPOSITIONS AND METHODS USING TRANSFORMING GROWTH FACTOR-BETA MIMICS | BHATNAGAR RAJENDRA S (US) | 2007-01-04 | — | — | WO | disclosed |
| EP-1261611-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1196436-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001064678-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001002424-A2 | PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |