Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324473 | 0.80 | L3MBTL1 (0.35) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL4575373 | 0.76 | MAPT (0.37) | MAPTALDH1A1POLBHTTKDM4E | |
| SCHEMBL4576154 | 0.73 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1POLBHTT | |
| SCHEMBL11982518 | 0.70 | KMT2A (0.50) | MAPTKMT2AALDH1A1POLBHTT | |
| SCHEMBL5289525 | 0.70 | PTPRA (0.37) | MAPTKMT2AALDH1A1 | |
| SCHEMBL3977606 | 0.68 | MAPT (0.47) | MAPTALDH1A1POLBHTTKDM4E | |
| SCHEMBL4000254 | 0.66 | MAPT (0.40) | MAPTKMT2AALDH1A1POLBHTT | |
| SCHEMBL12824763 | 0.66 | KMT2A (0.40) | MAPTKMT2AALDH1A1POLBHTT | |
| SCHEMBL10102749 | 0.66 | KMT2A (0.40) | MAPTKMT2AALDH1A1POLBHTT | |
| SCHEMBL11867402 | 0.66 | MAPT (0.43) | MAPTKMT2AALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925950-A | Process for preparing 1-hydroxyalkyl-5-nitroimidazole | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |